Rifapentine CAS No. 61379-65-5
Rifapentine is a rifamycin-class antibiotic used primarily in the treatment and prevention of tuberculosis (TB). As a long-acting antimicrobial agent, Rifapentine is essential in modern TB treatment regimens, especially in combination therapies. The compound is known for its enhanced half-life and improved patient compliance, making it highly valuable in public health programs worldwide.
Chemical Name: Rifapentine
CAS Number: 61379-65-5
Molecular Formula: C47H64N4O12
Molecular Weight: 877.04 g/mol
Pharmaceutical Grade: Active Pharmaceutical Ingredient (API)
Standard: USP / EP / CP compliant
Manufacturer: Zhengzhou Minzhong Pharmaceutical Co., Ltd
Why Choose Zhengzhou Minzhong Pharmaceutical for Rifapentine?
Zhengzhou Minzhong Pharmaceutical Co., Ltd is a leading pharmaceutical manufacturer with a strong reputation for quality, regulatory compliance, and global market distribution. Their Rifapentine is manufactured in GMP-certified facilities and exported to multiple countries across Asia, Africa, and Latin America.
Key Features:
- High Purity Rifapentine API
- Consistent Batch Quality
- Stringent In-House QC & QA
- Global Regulatory Documentation Support (DMF, CEP where applicable)
- Stable Supply Chain for Bulk Orders
Applications of Rifapentine
Rifapentine is widely used in:
- Short-course latent TB infection treatment (LTBI)
- Active tuberculosis treatment, in combination with other anti-TB drugs
- HIV/TB co-infection regimens, where drug-drug interactions are carefully managed
Its once-weekly dosing potential also makes Rifapentine a key player in preventive therapy protocols recommended by the WHO.
Product Specifications
| Parameter | Specification |
|---|---|
| Appearance | Reddish-orange powder |
| Assay (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residual Solvents | As per ICH Q3C guidelines |
| Heavy Metals | ≤ 10 ppm |
| Microbial Limits | Compliant with pharmacopeia |
Packaging & Storage
- Packaging: Fiber drums with double-layer PE bags; customizable options available.
- Storage Conditions: Store in a tightly sealed container, away from light and moisture, at room temperature.
- Shelf Life: 36 months under recommended storage conditions.
Global Supply & Partnering Opportunities
Zhengzhou Minzhong Pharmaceutical actively collaborates with:
- Global pharmaceutical companies
- Government health procurement agencies
- Non-profit healthcare organizations
- Contract development and manufacturing organizations (CDMOs)
With its strong supply infrastructure and dedicated export team, the company ensures on-time delivery and regulatory support for Rifapentine around the globe.
Request a Quote or Sample
If you’re seeking a reliable supplier of Rifapentine CAS No. 61379-65-5, Zhengzhou Minzhong Pharmaceutical Co., Ltd is your go-to source for bulk supply, consistent quality, and compliance-backed products.
👉 Visit Official Website: https://minzhong.ecbasis.com
📧 Contact Email: mzpharma@outlook.com
📞 Phone: +86-173 35350289
Rifapentine CAS No. 61379-65-5
A premier active pharmaceutical ingredient (API) for tuberculosis treatment, manufactured with an unwavering commitment to quality and excellence by Zhengzhou Minzhong Pharmaceutical Co Ltd.
A Vital Pharmaceutical Ingredient
In the global fight against tuberculosis (TB), effective and reliable APIs are paramount. Rifapentine stands as a crucial compound in this battle, known for its potent antibacterial activity. This application provides a definitive guide to Rifapentine, exploring its significance, applications, and why sourcing from Zhengzhou Minzhong ensures excellence.
From API to Patient Impact
This section illustrates the journey of our Rifapentine API from production to its critical role in healthcare. Click each step to see its importance in the value chain.
Our API is produced in state-of-the-art, GMP-compliant facilities.
Technical Profile
This section details the chemical properties, mechanism of action, and therapeutic uses of Rifapentine, providing essential information for researchers and formulators.
Understanding Rifapentine
Rifapentine is a rifamycin antibiotic pivotal in treating tuberculosis. The **CAS No. 61379-65-5** precisely identifies this compound, ensuring clarity in global trade and research. Its long half-life allows for less frequent dosing, significantly improving patient adherence to treatment.
Therapeutic Applications
- ✓ Latent TB Infection (LTBI): Used in highly effective, shorter regimens to prevent progression to active TB disease.
- ✓ Active Tuberculosis: A key component in combination regimens for drug-susceptible cases, helping shorten treatment durations.
Mechanism of Action
Rifapentine works by inhibiting a critical bacterial enzyme. Click the stages below to visualize the process.
1. Target Identification
Rifapentine targets the DNA-dependent RNA polymerase enzyme in *Mycobacterium tuberculosis*.
2. Inhibition
It binds to the enzyme, physically blocking it from synthesizing RNA.
3. Suppression of Synthesis
Without RNA synthesis, the bacterium cannot produce essential proteins.
4. Bacterial Death
This leads to the suppression of bacterial growth and ultimately cell death.
Our Commitment to Excellence
This section outlines the four pillars of our operational philosophy. Click each card to explore how we ensure that every batch of Rifapentine meets the highest global standards.
Quality Assurance
Our API is manufactured under stringent quality control systems that adhere to the highest international pharmaceutical standards, including GMP compliance and comprehensive batch testing.
Manufacturing Excellence
We leverage cutting-edge technology and optimized synthesis processes to produce Rifapentine efficiently and consistently, ensuring high yields and reliable supply capacity.
Reliable Supply Chain
With robust production capabilities and efficient logistics, we ensure timely delivery to clients worldwide, minimizing supply disruptions and supporting your production schedules.
Expertise & Experience
Our team possesses deep expertise in the synthesis and purification of complex pharmaceutical compounds, backed by years of experience and a commitment to continuous innovation.
Specifications & Documentation
We provide comprehensive documentation to support your quality control and regulatory needs. Our Rifapentine consistently meets or exceeds major pharmacopoeial requirements.
- Certificate of Analysis (CoA) Available
- Material Safety Data Sheet (MSDS) Available
- Technical Data Sheet (TDS) Available
- Drug Master File (DMF) Available
Partner with a Leader in API Manufacturing
Whether you are a pharmaceutical company, research institution, or distributor, we are equipped to meet your demands for high-quality Rifapentine.
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